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How to Use Weight Loss Injection Pens Weight loss injection pens are typically injected under the skin in the abdomen, thigh, or upper arm. The injection site should be rotated daily to avoid skin irritation. Who Is a Candidate for Weight Loss Injection Pens? Weight loss injection pens are approved for use in adults with obesity (BMI ≥30) or overweight (BMI ≥27) who have at least one weight-related medical condition, such as type 2 diabetes, high blood pressure, or high cholesterol. They are also approved for use in children and adolescents aged 12 and older with obesity. Benefits of Weight Loss Injection Pens Weight loss injection pens offer a number of benefits, including: They can help people lose weight and keep it off. They are relatively easy to use and can be injected at home. They are generally well-tolerated and have a low risk of serious side effects. They can be used to improve blood sugar control in people with type 2 diabetes. They can reduce the risk of heart disease a